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✦ Primal PointsA ONCE-DAILY ASHWAGANDHA BLEND FOR STRESS MANAGEMENT
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Adults, as a dietary supplement, take one capsule daily, preferably one capsule with breakfast, or as recommended by your healthcare provider.
For best results, take consistently and combine with a healthy routine that includes balanced meals, exercise, water, and plenty of rest.
Hypromellose (Capsule), Magnesium Stearate, Silica, Microcrystalline Cellulose.
Food supplement should not be used instead of a varied
balanced diet and healthy lifestyle.
1. As your body adapts to your new supplement routine, it’s important to remember that every individual is different and health benefits may vary from person to person. Always consult with your physician before using this or any other product if you have a preexisting condition or take prescription medication.
2. If you are pregnant, nursing, taking medication, or have an existing condition, be sure to consult with your physician before taking this or any other dietary supplement.
This unique stress relief formula features Prolanza™ Ashwagandha, a clinically-backed ashwagandha extract shown to support a wide range of benefits, from stress resilience to energy and memory. Participants of a randomized double-blind placebo-controlled clinical study reported an improvement in stress management, overall mood, sleep quality, and focus.*
Ashwagandha supplements are typically recommended to be consumed multiple times a day. This is where Prolanza™ stands out. Thanks to Prolanza™’s innovative delayed sustained-release technology, potent withanolides are released slowly throughout the day to provide continuous support for stress management. That means you can enjoy all the benefits of this premium ashwagandha all day long with just one single daily dose.*
Primal Stress Relief combines the potent power of Prolanza™ Ashwagandha with vitamin B6 and other adaptogens, including Rhodiola rosea, L-Theanine, and theobromine.*
Stress-supporting Rhodiola rosea, L-theanine, and vitamin B6 work together with focus-boosting theobromine to counter the impact of mental tension to help keep you calm and collected.*
Prolanza™ Ashwagandha is specially formulated to be highly absorbable due to its superior bioavailability. It delivers over 20 withanolides, the active ingredient in ashwagandha, for maximum potency.*
This premium ashwagandha extract is pure ashwagandha root to ensure maximum efficacy and benefits. It contains a high withanolide content, featuring between 4-5% withanolides. Prolanza™ Ashwagandha is always tested against the USP standard, the industry gold standard.*
This unique stress-soother is the first of its kind to deliver long-lasting benefits of ashwagandha in a single, once-a-day capsule.*
Adaptogens are herbs that help our bodies react to or recover from physical or mental stressors. These supplements may have a positive effect on mood, stress levels, fatigue, mental performance, and focus.*
Primal Stress Relief is a natural supplement that has been expertly formulated to support stress management. It contains the perfect blend of adaptogens, vitamin B6, and L-theanine essential for a calm and clear mind.*
Primal Stress Relief is a stress support formula, intended to help keep you calm and collected. It delivers a holistic, all-natural blend of premium ingredients without unwanted or harsh fillers. It even comes with a 90-day money-back guarantee, and every product is made in the USA and is third-party lab-tested for safety, purity, and effectiveness.
Primal Stress Relief is perfectly formulated for healthy adults and made to suit many different dietary needs and lifestyles. This formula is not made with eggs, gluten, soy, or dairy. We always recommend reading the label closely to ensure that this supplement is the right choice for your lifestyle and be sure to check with your doctor when in doubt.
Primal Stress Relief comes in easy-to-swallow capsules that are taken once daily (or as needed). Simply take one capsule daily with a meal. For best results, use consistently each day.
Each bottle of Primal Stress Relief contains 30 capsules, or a one-month supply if taken daily.
This product is manufactured in a facility that also processes tree nuts, peanuts, wheat, and soy. Always review the details on the product label for the most accurate information and when in doubt, we always recommend consulting with a personal physician regarding existing allergies or health concerns.
This product is intended for use by healthy adults over the age of 18. If you have a pre-existing condition, take prescription medications, or have any medical concerns, we always recommend consulting with your personal physician before starting a new supplement routine.
For maximum efficacy and shelf life, please store your Primal Stress Relief in a cool, dry place away from moisture, direct sunlight, and extreme temperatures.
If stored properly and unopened, Primal Stress Relief should generally retain its shelf life for about two years. Once opened, we recommend using the product within 90 days for maximum effectiveness. Each bottle contains a 30-day supply if taken daily.
Primal Stress Relief is formulated and manufactured in the USA in a GMP-certified facility (Good Manufacturing Practices) according to the highest safety and quality regulations. It is independently third-party lab-tested in the USA and is formulated with premium globally sourced ingredients (both domestic and imported) to ensure we use only the best ingredients available worldwide.†
*These statements have not been evaluated by the FDA Food & Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. The information provided by this website or this company is not a substitute for a face-to-face consultation with your physician and should not be construed as individual medical advice. The testimonials on this website are individual cases and do not guarantee that you will get the same results. All content, including text, graphics, images and information, contained on or available through this web site is for general information purposes only.
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STRESS MANAGEMENT AND THE ROLE OF RHODIOLA ROSEA: A REVIEWAnghelescu IG, Edwards D, Seifritz E, Kasper S. Stress management and the role of Rhodiola rosea: a review. Int J Psychiatry Clin Pract. 2018;22(4):242-252. doi:10.1080/13651501.2017.1417442
EFFECT OF ASHWAGANDHA (WITHANIA SOMNIFERA) EXTRACT ON SLEEP: A SYSTEMATIC REVIEW AND META-ANALYSISCheah KL, Norhayati MN, Husniati Yaacob L, Abdul Rahman R. Effect of Ashwagandha (Withania somnifera) extract on sleep: A systematic review and meta-analysis. PLoS One . 2021;16(9):e0257843. Published 2021 Sep 24. doi:10.1371/journal.pone.0257843
EFFICACY AND SAFETY OF ASHWAGANDHA (WITHANIA SOMNIFERA (L.) DUNAL) ROOT EXTRACT IN IMPROVING MEMORY AND COGNITIVE FUNCTIONSChoudhary D, Bhattacharyya S, Bose S. Efficacy and Safety of Ashwagandha (Withania somnifera (L.) Dunal) Root Extract in Improving Memory and Cognitive Functions. J Diet Suppl. 2017;14(6):599-612. doi:10.1080/19390211.2017.1284970
B6-RESPONSIVE DISORDERS: A MODEL OF VITAMIN DEPENDENCYClayton PT. B6-responsive disorders: a model of vitamin dependency. J Inherit Metab Dis. 2006;29(2-3):317-326. doi:10.1007/s10545-005-0243-2.
THE EFFECTS OF RHODIOLA ROSEA L. EXTRACT ON ANXIETY, STRESS, COGNITION AND OTHER MOOD SYMPTOMSCropley M, Banks AP, Boyle J. The Effects of Rhodiola rosea L. Extract on Anxiety, Stress, Cognition and Other Mood Symptoms. Phytother Res. 2015 Dec;29(12):1934-9. doi: 10.1002/ptr.5486. Epub 2015 Oct 27. PMID: 26502953.
EFFECTS OF TYROSINE ON COGNITIVE FUNCTION AND BLOOD PRESSURE UNDER STRESSDeijen JB, Orlebeke JF. Effect of tyrosine on cognitive function and blood pressure under stress. Brain Res Bull. 1994;33(3):319-23. doi: 10.1016/0361-9230(94)90200-3. PMID: 8293316.
HEALTH BENEFITS OF METHYLXANTHINES IN CACAO AND CHOCOLATEFranco R, Oñatibia-Astibia A, Martínez-Pinilla E. Health benefits of methylxanthines in cacao and chocolate. Nutrients. 2013;5(10):4159-4173. Published 2013 Oct 18. doi:10.3390/nu5104159.
THE COMBINATION OF L-THEANINE AND CAFFEINE IMPROVES COGNITIVE PERFORMANCE AND INCREASES SUBJECTIVE ALERTNESSGiesbrecht T, Rycroft JA, Rowson MJ, De Bruin EA. The combination of L-theanine and caffeine improves cognitive performance and increases subjective alertness. Nutr Neurosci. 2010;13(6):283-290. doi:10.1179/147683010X12611460764840.
EFFICACY AND SAFETY OF ASHWAGANDHA ROOT EXTRACT ON COGNITIVE FUNCTIONS IN HEALTHY, STRESSED ADULTS: A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY.Gopukumar K, Thanawala S, Somepalli V, Rao T. S. S, Thamatam VB, Chauhan S. Efficacy and Safety of Ashwagandha Root Extract on Cognitive Functions in Healthy, Stressed Adults: A Randomized, Double-Blind, Placebo-Controlled Study. Evidence-Based Compl Alt Med, vol. 2021. doi:10.1155/2021/8254344.
REVIEW OF THE ROLE OF HYPERHOMOCYSTEINEMIA AND B-VITAMIN DEFICIENCY IN NEUROLOGICAL AND PSYCHIATRIC DISORDERS – CURRENT EVIDENCE AND PRELIMINARY RECOMMENDATIONSHerrmann W, Lorenzl S, Obeid R. Hyperhomocysteinämie und B-Vitaminmangel bei neurologischen und psychiatrischen Erkrankungen--Aktueller Kenntnisstand und vorläufige Empfehlungen [Review of the role of hyperhomocysteinemia and B-vitamin deficiency in neurological and psychiatric disorders--current evidence and preliminary recommendations]. Fortschr Neurol Psychiatr. 2007;75(9):515-527. doi:10.1055/s-2007-980112
VITAMIN B6 LEVEL IS ASSOCIATED WITH SYMPTOMS OF DEPRESSIONHvas AM, Juul S, Bech P, Nexø E. Vitamin B6 level is associated with symptoms of depression. Psychother Psychosom. 2004;73(6):340-343. doi:10.1159/000080386
MULTICENTER, OPEN-LABEL, EXPLORATORY CLINICAL TRIAL WITH RHODIOLA ROSEA EXTRACT IN PATIENTS SUFFERING FROM BURNOUT SYMPTOMSKasper S, Dienel A. Multicenter, open-label, exploratory clinical trial with Rhodiola rosea extract in patients suffering from burnout symptoms. Neuropsychiatr Dis Treat. 2017;13:889-898. Published 2017 Mar 22. doi:10.2147/NDT.S120113
EFFICACY AND TOLERABILITY OF ASHWAGANDHA ROOT EXTRACT IN THE ELDERLY FOR IMPROVEMENT OF GENERAL WELL-BEING AND SLEEP: A PROSPECTIVE, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDYKelgane SB, Salve J, Sampara P, Debnath K. Efficacy and Tolerability of Ashwagandha Root Extract in the Elderly for Improvement of General Well-being and Sleep: A Prospective, Randomized, Double-blind, Placebo-controlled Study. Cureus. 2020;12(2):e7083. Published 2020 Feb 23. doi:10.7759/cureus.7083
RHODIOLA ROSEA IN SUBJECTS WITH PROLONGED OR CHRONIC FATIGUE SYMPTOMS: RESULTS OF AN OPEN-LABEL CLINICAL TRIALLekomtseva Y, Zhukova I, Wacker A. Rhodiola rosea in Subjects with Prolonged or Chronic Fatigue Symptoms: Results of an Open-Label Clinical Trial. Complement Med Res. 2017;24(1):46-52. doi:10.1159/000457918
AARP’S SURVEY ON SUPPLEMENTS FOR BRAIN HEALTHLevine H. AARP's Survey on Supplements for Brain Health. AARP. https://www.aarp.org/health/drugs-supplements/info-2019/brain-supplements-survey.html. June 11, 2019. Accessed June 7 2021.
AN INVESTIGATION INTO THE STRESS-RELIEVING AND PHARMACOLOGICAL ACTIONS OF AN ASHWAGANDHA (WITHANIA SOMNIFERA) EXTRACT: A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDYLopresti AL, Smith SJ, Malvi H, Kodgule R. An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo-controlled study. Medicine (Baltimore). 2019;98(37):e17186. doi:10.1097/MD.0000000000017186
RHODIOLA ROSEA VERSUS SERTRALINE FOR MAJOR DEPRESSIVE DISORDER: A RANDOMIZED PLACEBO-CONTROLLED TRIALMao JJ, Xie SX, Zee J, et al. Rhodiola rosea versus sertraline for major depressive disorder: A randomized placebo-controlled trial. Phytomedicine. 2015;22(3):394-399. doi:10.1016/j.phymed.2015.01.010
THE RELEVANCE OF THEOBROMINE FOR THE BENEFICIAL EFFECTS OF COCOA CONSUMPTIONMartínez-Pinilla E, Oñatibia-Astibia A, Franco R. The relevance of theobromine for the beneficial effects of cocoa consumption. Front Pharmacol. 2015;6:30. Published 2015 Feb 20. doi:10.3389/fphar.2015.00030
NEUROBIOLOGICAL AND SYSTEMIC EFFECTS OF CHRONIC STRESSMcEwen, Bruce S. “Neurobiological and Systemic Effects of Chronic Stress.” Chronic stress (Thousand Oaks, Calif.) vol. 1 (2017): 2470547017692328. doi:10.1177/2470547017692328.
VITAMIN B6 IS ASSOCIATED WITH DEPRESSIVE SYMPTOMATOLOGY IN MASSACHUSETTS ELDERSMerete C, Falcon LM, Tucker KL. Vitamin B6 is associated with depressive symptomatology in Massachusetts elders. J Am Coll Nutr. 2008;27(3):421-427. doi:10.1080/07315724.2008.10719720.
THE ROLE OF B VITAMINS IN PREVENTING AND TREATING COGNITIVE IMPAIRMENT AND DECLINEMorris, Martha Savaria. “The role of B vitamins in preventing and treating cognitive impairment and decline.”Advances in nutrition (Bethesda, Md.) vol. 3,6 801-12. 1 Nov. 2012, doi:10.3945/an.112.002535.
A SYSTEMATIC REVIEW OF THE CLINICAL USE OF WITHANIA SOMNIFERA (ASHWAGANDHA) TO AMELIORATE COGNITIVE DYSFUNCTIONNg QX, Loke W, Foo NX, et al. A systematic review of the clinical use of Withania somnifera (Ashwagandha) to ameliorate cognitive dysfunction. Phytother Res. 2020;34(3):583-590. doi:10.1002/ptr.6552
L-THEANINE, A NATURAL CONSTITUENT IN TEA, AND ITS EFFECT ON MENTAL STATENobre AC, Rao A, Owen GN. L-theanine, a natural constituent in tea, and its effect on mental state. Asia Pac J Clin Nutr. 2008;17 Suppl 1:167-168.
EFFECT OF MAGNESIUM AND VITAMIN B6 SUPPLEMENTATION ON MENTAL HEALTH AND QUALITY OF LIFE IN STRESSED HEALTHY ADULTS: POST-HOC ANALYSIS OF A RANDOMISED CONTROLLED TRIALNoah L, Dye L, Bois De Fer B, Mazur A, Pickering G, Pouteau E. Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial. Stress Health. 2021;37(5):1000-1009. doi:10.1002/smi.3051
RELATIONSHIP OF NEUROTRANSMITTERS TO THE SYMPTOMS OF MAJOR DEPRESSIVE DISORDERNutt DJ. Relationship of neurotransmitters to the symptoms of major depressive disorder. J Clin Psychiatry. 2008;69 Suppl E1:4-7.
SALIDROSIDE, A BIOACTIVE COMPOUND OF RHODIOLA ROSEA, AMELIORATES MEMORY AND EMOTIONAL BEHAVIOR IN ADULT MICEPalmeri A, Mammana L, Tropea MR, Gulisano W, Puzzo D. Salidroside, a Bioactive Compound of Rhodiola Rosea, Ameliorates Memory and Emotional Behavior in Adult Mice. J Alzheimers Dis. 2016;52(1):65-75. doi:10.3233/JAD-151159
L-THEANINE RELIEVES POSITIVE, ACTIVATION, AND ANXIETY SYMPTOMS IN PATIENTS WITH SCHIZOPHRENIA AND SCHIZOAFFECTIVE DISORDER: AN 8-WEEK, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, 2-CENTER STUDYRitsner MS, Miodownik C, Ratner Y, et al. L-theanine relieves positive, activation, and anxiety symptoms in patients with schizophrenia and schizoaffective disorder: an 8-week, randomized, double-blind, placebo-controlled, 2-center study. J Clin Psychiatry. 2011;72(1):34-42. doi:10.4088/JCP.09m05324gre
ADAPTOGENIC AND ANXIOLYTIC EFFECTS OF ASHWAGANDHA ROOT EXTRACT IN HEALTHY ADULTS: A DOUBLE-BLIND, PLACEBO-CONTROLLED CLINICAL STUDYSalve J, Pate S, Debnath K, Langade D. Adaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults: A Double-blind, Randomized, Placebo-controlled Clinical Study. Cureus. 2019;11(12):e6466. Published 2019 Dec 25. doi:10.7759/cureus.6466.
A RANDOMIZED TRIAL OF TWO DIFFERENT DOSES OF A SHR-5 RHODIOLA ROSEA EXTRACT VERSUS PLACEBO AND CONTROL CAPACITY FOR MENTAL WORKShevtsov VA, Zholus BI, Shervarly VI, Vol'skij VB, Korovin YP, Khristich MP, Roslyakova NA, Wikman G. A randomized trial of two different doses of a SHR-5 Rhodiola rosea extract versus placebo and control of capacity for mental work. Phytomedicine. 2003 Mar;10(2-3):95-105. doi: 10.1078/094471103321659780. PMID: 12725561.
MONOAMINE OXIDASE INHIBITION BY RHODIOLA ROSEA L. ROOTSvan Diermen D, Marston A, Bravo J, Reist M, Carrupt PA, Hostettmann K. Monoamine oxidase inhibition by Rhodiola rosea L. roots. J Ethnopharmacol. 2009 Mar 18;122(2):397-401. doi: 10.1016/j.jep.2009.01.007. Epub 2009 Jan 9. PMID: 19168123.
THE EFFECTS OF GREEN TEA AMINO ACID L-THEANINE CONSUMPTION ON THE ABILITY TO MANAGE STRESS AND ANXIETY LEVELS: A SYSTEMATIC REVIEWWilliams JL, Everett JM, D'Cunha NM, et al. The Effects of Green Tea Amino Acid L-Theanine Consumption on the Ability to Manage Stress and Anxiety Levels: a Systematic Review. Plant Foods Hum Nutr. 2020;75(1):12-23. doi:10.1007/s11130-019-00771-5.
ROSENROOT (RHODIOLA): POTENTIAL APPLICATIONS IN AGING-RELATED DISEASESZhuang W, Yue L, Dang X, et al. Rosenroot (Rhodiola): Potential Applications in Aging-related Diseases. Aging Dis. 2019;10(1):134-146. Published 2019 Feb 1. doi:10.14336/AD.2018.0511.
