Primal Immune Defense

THE ALL-IN-ONE IMMUNE SUPPORT FORMULA*

Primal Immune Defense Primal Immune Defense Primal Immune Defense Primal Immune Defense
Primal Immune Defense
Primal Immune Defense
Primal Immune Defense
Primal Immune Defense
Primal Immune Defense
Primal Immune Defense
Primal Immune Defense
Primal Immune Defense
Primal Immune Defense
Primal Immune Defense

THE ALL-IN-ONE IMMUNE SUPPORT FORMULA*

  • Doctor-formulated for maximum effectiveness*
  • Featuring zinc and essential vitamins C, B6, D3, and K
  • Supports healthy immune function and general wellness*
  • 14 billion CFUs of L. acidophilus and Bb-06 probiotics
  • With reishi and lion's mane mushrooms*
  • Gluten-free, soy-free, and gelatin-free
  • Made in the USA with globally sourced ingredients
Money-Back Guarantee
90-Day

Primal Immune Defense


$23.96 $29.95 per month
Select Quantity
Purchase Options
Flexible Flexible subscription plan
Cancel Easy cancel anytime

➜  Learn more about subscription

OTP
Switch to a subscription and save $-2366.05

You can have the same for only $2396. Convenient way to get Free Shipping and best prices. You can change or cancel your subscription any time!

Switch to a subscription for a convenient hassle-free delivery

Free delivery of all recurring shipments. You can change or cancel your subscription any time!

You save
$5.99

In Stock In Stock, Ready to Ship

Payment methods
All transaction secured and encrypted

For questions or phone orders call: 631-769-2227

THE ALL-IN-ONE IMMUNE SUPPORT FORMULA*

  • Doctor-formulated for maximum effectiveness*
  • Featuring zinc and essential vitamins C, B6, D3, and K
  • Supports healthy immune function and general wellness*
  • 14 billion CFUs of L. acidophilus and Bb-06 probiotics
  • With reishi and lion's mane mushrooms*
  • Gluten-free, soy-free, and gelatin-free
  • Made in the USA with globally sourced ingredients
  • 1
    FREE SHIPPING ON ORDERS OF $75 OR MORE
  • 2
    ORDERS BY 3PM SHIP SAME DAY (MON-FRI)†
  • 3
    90-DAY MONEY-BACK GUARANTEE
  • 4
    MADE IN THE USA WITH GLOBALLY SOURCED INGREDIENTS

You may also like

Primal Multivitamin

The best multivitamin for daily support

$29.95
Primal Omega 3

Premium omega-3 supplement formula

$36.95
Primal Probiotics

A comprehensive probiotic & prebiotic formula

$38.95
Primal Greens

A delicious greens powder with 50+ superfoods

$49.95
6 Core Benefits Of Our
PRIMAL IMMUNE DEFENSE
PRIMAL IMMUNE DEFENSE
Primal Harvest’s Immune Defense is a doctor-formulated 3-step solution for total immune system support.*
This easy-to-take formula features two premium probiotic strains to support gut health and overall wellness.*
Formulated with zinc and essential vitamins C, D3, B6, and K this immune support formula is a must-have in any wellness routine.*
This formula features GOS prebiotics to help keep the healthy gut bacteria thriving to support a balanced gut.*
Features adaptogenic mushrooms like reishi and organic lion’s mane for additional stress and wellness support.*
We’ve included the widely researched probiotic strain Lactobacillus acidophilus (LA-14) for additional gut and immune support.*
PRIMAL IMMUNE DEFENSE
HOW MIGHT I BENEFIT OVER TIME?*
Everybody is unique and we all respond differently to changes in our wellness routines. Like with any healthy habit, commitment is key to seeing the biggest results. Here are some examples of how adding daily immune support may look for different people:*
WHEN TAKEN
DAILY FOR 1 MONTH:
Some may experience enhanced energy and digestive benefits.*
WHEN TAKEN
DAILY FOR 2 MONTHS:
Some may notice more support for digestive concerns, energy levels, and feeling “run-down”.*
WHEN TAKEN
DAILY FOR 3+ MONTHS:
Some feel generally satisfied with their gut health, energy levels, and overall wellness.*
Effects
PRIMAL IMMUNE DEFENSE AS A SUBSCRIPTION
EVERY 30 DAYS TO YOUR HOME
Reaping the maximum benefits from our supplements has never been so simple. With our easy and convenient subscription service you can have your Primal Immune Defense delivered right to your front door every month.
HERE’S HOW OUR SUBSCRIBE & SAVE PROGRAM WORKS:
Subscription Info
SUBSCRIBE WITH CONFIDENCE
Choose how often you want to receive your products
Subscription Info
ENJOY FREE SHIPPING
Receive free shipping in the U.S., straight to your door
Subscription Info
RECEIVE BIG SAVINGS!
Save up to 20% on each recurring order
Subscription Info
CANCEL OR CHANGE ANYTIME
Flexible, hassle-free options to fit your needs
NATURE'S BEST
COMPLETE INGREDIENT TRANSPARENCY
Doctor-formulated with only the highest quality ingredients, this immune support complex features a blend of pre- and probiotics, mushroom extracts, and key vitamins and minerals.*
HOW TO USE
HOW TO USE

Adults, as a dietary supplement, take two capsules daily, preferably with a morning or afternoon meal, or as recommended by your healthcare provider.

For best results, combine with a healthy routine that includes balanced meals, exercise, water, and plenty of rest.

SUPPLEMENT FACTS
SUPPLEMENT FACTS
Supplement facts per serving

Vitamin C (as Ascorbic Acid), Vitamin D3, Vitamin K2 (as Menaquinone MK-7), Vitamin B6 (as Pyridoxine HCL), Zinc (as Zinc AAC), Reishi (Ganderma lucidum)(Fruiting Body) 20:1 Extract 10% Polysaccharides, GOS (Galacto-oligosaccharides), Organic Lion’s Mane Mushroom (Hericium erinaceus)(Mycelium / Fruit Body), Bifidobacterium bifidum Bb-06, Lactobacillus acidophilus La-14, BioperineⓇ Black Pepper (Piper nigrum) Fruit Extract 95% Piperine. 

Other Ingredients: Vegetable Cellulose (Capsule), Microcrystalline Cellulose, Organic Rice Concentrate, Vegetable Stearate.

1. As your body adapts to your new supplement routine, it’s important to remember that every individual is different and health benefits may vary from person to person. Always consult with your physician before using this or any other product if you have a preexisting condition or take prescription medication.

2. If you are pregnant, nursing, taking medication, or have an existing condition, be sure to consult with your physician before taking this or any other dietary supplement.

CORE INGREDIENTS

Primal Immune Defense is expertly formulated with pre- and probiotics. It contains two widely studied probiotic strains, Lactobacillus acidophilus (LA-14) and Bifidobacterium bifidum (Bb-06), and premium GOS prebiotics to help maintain a healthy immune system.*

Vitamins D3, B6, C, K, and the mineral zinc are vital for immune support. This doctor-formulated blend delivers these vitamins and minerals to keep you feeling your best.*

Primal Immune Defense is expertly crafted with black pepper extract for absorption support*

We’ve included reishi and organic lion’s mane to round out this immune support formula. Used traditionally for their wellness benefits, these mushrooms may help support energy and mood amongst other potential benefits.*

CORE INGREDIENTS
Primal Harvest Primal Harvest
DON'T TAKE OUR WORD FOR IT
HEAR WHAT OUR CUSTOMERS ARE SAYING!
Primal Harvest
FREQUENTLY ASKED QUESTIONS

Primal Immune Defense is a doctor-formulated immune support blend that takes a 360° holistic approach to supporting your wellness. Primal Immune Defense contains prebiotics, probiotics, mushroom extracts, vitamins, and zinc to provide your immune system with daily support and keep you ready to tackle whatever life throws your way.*

Probiotics are the so-called “good” or “friendly” bacteria that live in your gut. There are different types of probiotic strains that have been isolated and defined by scientists for their potential to support our health. Various strains have different effects on the body; some may support digestion, while others are thought to help support immune health.*

Primal Immune Defense helps you support a healthy immune system in a simple and convenient way. It combines key nutrients with probiotics and adaptogens to offer a all-round formula for immune health. Each serving delivers 500 mg of vitamin C, 25 mcg of vitamin D3, and 20 mg of zinc, plus vitamins K2 and B6. This formula delivers the probiotic strains Lactobacillus acidophilus (La-14) and Bifidobacterium bifidum to support gut health and a balanced gut microbiome. GOS prebiotics support the longevity of these probiotic strains. Extracts from reishi and organic lion’s mane mushrooms round out this easy-to-use supplement.*

We recommend that you take your 2 capsules daily with your morning breakfast, brunch, or afternoon lunch. Since consistency is key to getting the most out of your Immune Defense, we recommend picking a time and sticking to it each day.

Each bottle contains 30 servings (or a one-month supply).

This product is manufactured in a facility that also processes tree nuts, peanuts, wheat, and soy. Always review the label closely for the most accurate information, and check with your doctor if you have any concerns.

Primal Immune Defense is intended for use by healthy adults over 18 years old. We recommend that you consult with your physician before use if you are taking any prescription or over-the-counter medications or are being treated for any existing medical conditions.

We have formulated this product to be shelf-stable with a significant overage on total cell enumeration. Probiotic bacteria can be sensitive to certain environments, that’s why we keep them temperature controlled throughout the entire production process, including storage in our warehouse.

Although Primal Immune Defense is shelf-stable and specially formulated to maintain maximum efficiency and shelf life, we recommend storing it in a cool, dry place away from moisture, and outside of direct sunlight. Although it’s not required, you can refrigerate your product after opening.

Stability studies show that full potency and cell count will be maintained for 18+ months if stored properly and unopened. After 18 months, the probiotic is at risk of a decrease in potency and cell count. Once opened, we recommend finishing an opened bottle within 90 days and storing the opened bottle either in low-moisture conditions.

To take full advantage of our discounts and to help you remain consistent with your routine, we recommend buying multiple bottles of Primal Immune Defense. You are always protected by our 90-day money-back guarantee so you have plenty of time to enjoy the long term benefits of Primal Immune Defense and make sure it’s the right fit for you. Please have a look at “What is the shelf life of my Primal Immune Defense?” to learn more.

If you are using a discount code, please note that your discount code cannot be combined with any other offer or discount code and excludes all sale items and subscription purchases.

Our products are made in the USA with premium globally sourced ingredients to ensure we use only the best ingredients available worldwide. All our products are independently third-party laboratory tested to ensure safety, quality, and purity.

Note: The information provided by this website or this company is not a substitute for a face-to-face consultation with your physician and should not be construed as individual medical advice.  The testimonials on this website are individual cases and do not guarantee that you will get the same results. All content, including text, graphics, images, and information, contained on or available through this website is for general information purposes only.

DISCLAIMER: This scientific research is for informational purposes only. The results reported may not necessarily occur in all individuals. Primal Harvest provides this information as a service but does not endorse it. This information should not be read to recommend or endorse any specific products.

Abdullah N, Ismail SM, Aminudin N, Shuib AS, Lau BF. Evaluation of Selected Culinary-Medicinal Mushrooms for Antioxidant and ACE Inhibitory Activities. Evid Based Complement Alternat Med. 2012;2012:464238. doi:10.1155/2012/464238.

Aranow C. Vitamin D and the Immune System. J Investig Med. 2011 Aug;59(6):881-6. doi: 10.2310/JIM.0b013e31821b8755. PMID: 21527855; PMCID: PMC3166406.

Carr AC, Maggini S. Vitamin C and Immune Function. Nutrients. 2017 Nov 3;9(11):1211. doi: 10.3390/nu9111211. PMID: 29099763; PMCID: PMC5707683.

Chen L, Deng H, Cui H, et al. Inflammatory responses and inflammation-associated diseases in organs. Oncotarget. 2017;9(6):7204-7218. Published 2017 Dec 14. doi:10.18632/oncotarget.23208.

Di Rosa M, Malaguarnera M, Nicoletti F, Malaguarnera L. Vitamin D3: a helpful immuno-modulator. Immunology. 2011;134(2):123-139. doi:10.1111/j.1365-2567.2011.03482.x.

Ellulu MS, Rahmat A, Patimah I, Khaza'ai H, Abed Y. Effect of vitamin C on inflammation and metabolic markers in hypertensive and/or diabetic obese adults: a randomized controlled trial. Drug Des Devel Ther. 2015;9:3405-3412. Published 2015 Jul 1. doi:10.2147/DDDT.S83144.

Friedman M. Chemistry, Nutrition, and Health-Promoting Properties of Hericium erinaceus (Lion's Mane) Mushroom Fruiting Bodies and Mycelia and Their Bioactive Compounds. J Agric Food Chem. 2015;63(32):7108-7123. doi:10.1021/acs.jafc.5b02914.

Iijima H, Shinzaki S, Takehara T. The importance of vitamins D and K for the bone health and immune function in inflammatory bowel disease. Curr Opin Clin Nutr Metab Care. 2012;15(6):635-640. doi:10.1097/MCO.0b013e328357f623.

Lull C, Wichers HJ, Savelkoul HF. Antiinflammatory and immunomodulating properties of fungal metabolites. Mediators Inflamm. 2005;2005(2):63-80. doi:10.1155/MI.2005.63.

Macfarlane S. Prebiotics in the gastrointestinal tract. Bioactive Foods in Promoting Health. 2010:145-156. doi:10.1016/b978-0-12-374938-3.00010-4

Namazi, N., Larijani, B., Azadbakht, L. (2019). Vitamin K and the Immune System. In: Mahmoudi, M., Rezaei, N. (eds) Nutrition and Immunity. Springer, Cham. https://doi.org/10.1007/978-3-030-16073-9_4

Office of Dietary Supplements - Vitamin C. https://ods.od.nih.gov/factsheets/VitaminC-HealthProfessional/. Accessed March 4, 2021.

Prasad, A.S.. Zinc in Human Health: Effect Of Zinc on Immune Cells. Mol Med. 2008; 14(5-6): 353-357.

Qian, Bingjun et al. “Effects of Vitamin B6 Deficiency on the Composition and Functional Potential of T Cell Populations.” Journal of immunology research vol. 2017 (2017): 2197975. doi:10.1155/2017/2197975

Ruiz L, Delgado S, Ruas-Madiedo P, Sánchez B, Margolles A. Bifidobacteria and Their Molecular Communication with the Immune System. Front Microbiol. 2017;8:2345. Published 2017 Dec 4. doi:10.3389/fmicb.2017.02345.  

Shankar AH, Prasad AS. Zinc and immune function: the biological basis of altered resistance to infection. Am J Clin Nutr. 1998;68(2 Suppl):447S-463S. doi:10.1093/ajcn/68.2.447S.

Technical Memorandum: Lactobacillus Acidophilus La-14. Danisco. (6AD, January). Accessed March 4, 2021, http://ss1.spletnik.si/4_4/000/000/19f/152/La-14 TM.pdf.

Valverde ME, Hernández-Pérez T, Paredes-López O. Edible mushrooms: improving human health and promoting quality life. Int J Microbiol. 2015;2015:376387. doi:10.1155/2015/376387.

Wintergerst ES, Maggini S, Hornig DH. Immune-enhancing role of vitamin C and zinc and effect on clinical conditions. Ann Nutr Metab. 2006;50(2):85-94. doi: 10.1159/000090495. Epub 2005 Dec 21. PMID: 16373990.