Top 10 Supplements To Help Heal a Leaky Gut

May 23, 2020 8 min read

Did you know that our everyday modern lifestyles have been wreaking havoc on our gut microbiota and gut walls for years?

As our gut health continues to decline on a large scale, it’s no surprise that we’re seeing more and more widespread gut-related issues affecting people in some pretty major ways. 


Some of these lifestyle factors include eating more and more processed and sugary foods, increased stress, busier schedules, less sleep and physical activity, and consumption of more prescription medications than ever before (particularly antibiotics).


If you struggle with one or more gut-related issues, you’re most certainly not alone!


The unfortunate truth is that the majority of people have already battled at least one or more gut-related issues, even if they weren’t aware that the problem was stemming from their gut.


But for so many of us, gut issues are an everyday battle that leaves us uncomfortable, frustrated, and desperate for answers.


Especially with the addition of the current crisis, we are facing higher stress and anxiety levels than ever before, and our gut is most definitely paying the price as we do our best to cope with these unprecedented times.


Poor diet, unmanaged stress, and other unhealthy lifestyle habits like consuming large amounts of alcohol and junk food can lead to an overgrowth of bad bacteria in our gut, as well as severely damaging the strength of our gut barrier.


Supplements To Heal Gut


Why is your gut lining important?


Our gut is lined with a mix of protective cells and mucus, known as the “gut barrier” or “intestinal lining,” that work together to act as the  primary gatekeeper to the rest of your body.


This incredible protective intestinal lining within our bellies covers more than 4,000 square feet of surface area.


When your gut lining becomes damaged, it can cause what is known as “leaky gut” syndrome. It is also commonly referred to as “increased intestinal permeability”or “gut hyperpermeability.”


This issue arises as tightly bound junctions within your intestinal wall begin to become loose, allowing for uninspected foreign invaders to pass through your gut walls and into your bloodstream.


When your gut barrier is no longer able to effectively keep out harmful substances, these toxins can then begin ‘leaking’ out into the rest of your body. 


And this is where a long list of health concerns can arise, setting you on a path towards chronic illness and inflammation.


Your gut lining is your  final line of defense between your vital organs and harmful influences from the outside environment


The term “leaky gut” is actually still somewhat new amongst the medical community, and there is more research to be done as doctors and researchers continue to unravel the complexities of gut health and leaky gut syndrome. 


One thing that’s for certain is that the gut and gut lining are both more important than was once historically believed. A leaky gut is far more common than you might think, and it goes far beyond just digestive concerns.


Could you be struggling with a leaky gut and not even know it? 


Supplements Leaky Gut



  • Weak immune system
  • Joint pain or stiffness
  • Frequent sugar or carb cravings
  • Chronic fatigue
  • Lack of energy
  • Skin issues (acne, rosacea, eczema, rashes)
  • Frequent headaches
  • Seasonal allergies
  • Mood swings/anxiety/depression
  • Bloating, diarrhea, constipation
  • Nutritional deficiencies
  • Hormonal imbalances (PMS, PCOS, etc)
  • Food allergies or intolerances
  • Trouble concentrating, memory loss, or brain fog


Our food choices, along with infections, toxins, and stress, are usually the top three factors to look at when it comes to addressing the problems causing a leaky gut.


How can I heal a leaky gut?

Adopting a healthier lifestyle and adding a few key supplements to your daily routine has been shown to do wonders for healing a leaky gut and decreasing negative symptoms associated with this health concern. 

The below supplements target and decrease chronic inflammation in the gut and intestinal walls and can help restore strength and balance to a leaky gut.


Even better, many of these supplements are multifunctional, and can help heal other issues occuring within your gut simultaneously. 


Here are 10 supplements that may help deliver essential nutrients to your gut, and allow it to naturally repair your gut mucosal lining.


Supplements Heal Gut

Top 10 Supplements to
Help Heal a Leaky Gut

1. Pre & Probiotics

At least  70% of your immune system’s cells and at least 90% of your body’s serotonin (the “happy chemical”) is produced in the digestive tract. In other words, maintaining a healthy balance of "good" bacteria in your gut microbiota is absolutely essential to good health, and a vital part of preventing a leaky gut. 

Prebiotics are the fuel that feed probiotics, which are healthy microbes that promote the growth and balance of more “good” bacteria within your gut. Probiotics have been shown to assist in the protection and reinstitution of a healthy gut barrier in clinical studies.

We've included 3 billion CFU’s of premium patented B. longum BB536® probiotics in our brand new Primal Gut Restore to help provide multifunctional healing benefits to both your microbiome and gut lining. 


2. Postbiotics

Many researchers are now beginning to discover that many of the gut-healing benefits we attribute to probiotics are largely due to a substance known as postbiotics. A fairly new term in the '-biotic' world, postbiotics are the 'waste' that's produced when prebiotics feed on probiotics. 

The final and most crucial step, our Primal Gut Restore features revolutionary patented  CoreBiome® Tributyrin, the single most important and groundbreaking postbiotic on the market.

CoreBiome® is a patented form of a short chain fatty acid known as ‘butyrate’. If you haven’t heard of butyrate before, it’s important to know that it's considered the most important energy source for the cells in your gut lining, and it’s naturally produced by healthy bacteria in your gut.

Whereas most forms of butyrate are quickly used up by the stomach or small intestine, CoreBiome® is specially designed to get directly to your colon, where it’s most crucial for immune and overall health support. It's also one of the most powerful tools for healing a leaky gut

CoreBiome® is the first of its kind to be clinically proven to stimulate butyrate-producing bacteria, as well as boost butyrate production in the colon.


3. Digestive Enzymes

Digestive enzymes are a great option for helping to support overall digestive health. Responsible for making sure that your body fully breaks down proteins, fats, and carbohydrates during digestion, these enzymes prevent your gut lining from confusing undigested food particles are 'foreign invaders' and sparking more inflammation.

These enzymes come in many different forms and have been shown to reduce symptoms of a leaky gut, as well as prevent wear and tear of your gut lining.


4. Curcumin

The highly popular superfood known as turmeric is a well-known antioxidant and powerful anti-inflammatory in the holistic health world. The main healing compound in turmeric, known as curcumin, has been studied for its ability to promote healthy inflammatory responses in the body and support overall wellness.

When it comes to healing a leaky gut, some studies have shown that a high quality turmeric extract (like our Turmeric Complexmay help strengthen the gut barrier by contracting the loosened proteins in this lining. Squeezing the cells closer together helps to restore a healthy, functional gut lining and reduce gut permeability. 


5. Collagen Peptides

Collagen is believed to be beneficial to your gut lining for a variety of different reasons. The 'glue' that holds us together, collagen is your body's primary protein and, made up of amino acids, is the fundamental building block for your entire skeleton.

Adding a collagen peptide powder or collagen bone broth to your daily routine can help reintroduce some of this vital collagen and reduce symptoms associated with a leaky gut. 


Supplements To Heal Gut


6. Vitamin D

This important vitamin is essential for healthy immune system function and may also help decrease intestinal permeability associated with a leaky gut and IBS symptoms. Studies have shown that getting plenty of vitamin D (from natural sunlight or food sources) may help to reduce leaky gut symptoms, such as constipation, cramping, bloating, and diarrhea. 


7. L-Glutamine

This amino acid is naturally produced by your gut and is the most common amino in your body. It's main functions in the body are to help repair the intestinal lining, reduce gut inflammation, and decrease intestinal permeability associated with a leaky gut. Many studies have also shown that L-Glutamine may help decrease IBS symptoms and digestive issues and promote rapid healing within the gut.

It is often considered to be one of the most important factors for healing a leaky gut, by enabling vital enterocytes (gut cells) to repair themselves more quickly.


8. Zinc

Some studies have shown that the essential mineral zinc may also help heal a leaky gut by easing symptoms such as constipation and diarhea, and helping restore the gut mucosal lining to a healthy state.


9. Fish Oil

Few nutritional elements have been studied as thoroughly as the essential omega-3 fatty acids in supplements such as our Primal Omega-3 fish oilThe DHA & EPA found in omega-3's has been thoroughly researched for their many health benefits, from promoting healthy eye, brain, skin, and joint health, as well as helping support healthy inflammatory responses.

By helping to reduce gut wall inflammation, omega-3 fatty acids may also help repair a leaky gut. Eating an omega-rich diet or supplementing with quality fish oil supplements is the best way to experience the many gut-healing benefits of these vital fatty acids.


10. Slippery Elm

Studies have shown that some natural remedies, like this calming, soothing herb, can help ease symptoms associated with a leaky gut. Slippery elm, along with others like marshmallow root, provide a therapeutic and multifunctional effect that may help calm the intestinal lining. 


Getting to the root cause of the issues damaging your gut lining is the first major step towards restoring balance to so many areas of your health.


A healthier gut and stronger gut barrier prevents harmful toxins from leaking out into your bloodstream, and increasing your risk for a number of various chronic diseases.


One the best things you can do for your overall health, boosting your gut health and healing a leaky gut will allow you to feel your best and live your best life, at any age!


Not sure where to begin? Not to worry! If all of these supplement options seem overwhelming or time-consuming, we recommend sticking to the top three most important supplements to begin: Probiotics, Postbiotics, and Digestive Enzymes.


If you then require some additional gut support later on, or it’s recommended by a healthcare professional, you can add additional options or experiment with other supplements.


And most importantly, don’t forget that supplements alone won’t do you much good if you’re consistently leading an unhealthy lifestyle.


Combining your supplements with healthy holistic lifestyle choices, like drinking plenty of water, eating a balanced anti-inflammatory diet, proper stress reduction, and getting plenty of rest, will ensure you get the most out of your supplements.


In other words, you can actually help your body to better absorb your gut-healing supplements, and produce more effective results.







Jennifer Sluzewski
Written by
Jennifer Sluzewski

Writer and Content Creator for Team Primal Harvest
As a former JMU Duke and graduate of the School of Media Arts and Design, Jennifer has been a writer and editor for multiple brands and publications over the past eight years. Currently residing in NYC, she can often be found in a coffee shop, yoga studio, or planning her next travel adventure!